Osthole 藥理作用
WebAbstract. Context: Osthole is a natural coumarin compound most frequently extracted from plants of the Apiaceae family such as Cnidium monnieri (L.) Cusson, Angelica pubescens … WebApr 21, 2024 · Objective . To study the mechanism of osthole in GC based on network pharmacology and molecular docking. Methods . The potential targets of osthole were predicted through the TCM System Pharmacology Analysis Platform, SwissTargetPrediction, and PharmMapper database. Targets related to gastric cancer were obtained through …
Osthole 藥理作用
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WebAug 1, 2015 · Background Hepatic fibrosis is a dynamic process which ultimately leads to cirrhosis in almost patients with chronic hepatic injury. However, progressive fibrosis is a reversible scarring response. Activation of hepatic stellate cells (HSCs) is the prevailing process during hepatic fibrosis. Osthole is an active component majorly contained in the … WebApr 21, 2024 · Objective . To study the mechanism of osthole in GC based on network pharmacology and molecular docking. Methods . The potential targets of osthole were …
WebJan 17, 2024 · Up to date, there is no report of osthole’s side effects on cancer treatment, so osthole is a safety and effective tumor suppressor. Moreover, osthole could successfully inhibit tumor synergistically with a relatively low and safe Gy X-ray radiations for cellular or animal model, since we did not find any side effects for all mice treatment with X-ray …
Web第十五局改正日本薬局方適合生薬試験用 (標品) オストール. オストールはジャショウシの確認試験用標品です。. ジャショウシはオカゼリ科の果実で、収れん性消炎薬として用い … WebActive constituent of Cnidium monnieri, a traditional Chinese medicine used for its anti-inflammatory, analgesic, and anti-lipedemic activities.Dramatically decreased lipid accumulation in a quail model. Its neuroprotective effect on MPP(+)-induced cytotoxicity in PC12 cells supports the use of osthole as a therapeutic agent for the treatment of …
WebOsthole, an O-methylated coumarin, exhibits a myriad of biochemical properties and its derivative, furo [3,2-c ]coumarin is capable of forming covalent bonds with DNA and other biological macromolecules, 72 e.g., Wedelolactone (antihepatotoxic), 73 Angelicin (anticancer, antiviral, anti-inflammatory) 74–76.
WebNov 20, 2024 · Osthole has a central sedative effect and can improve the learning and memory function of mice. 4. Osthole presents the effect of relieving asthma by regulating … link your iphone to your windows pcWebApr 24, 2024 · In the current study, we identified a plant compound, osthole that inhibits mast cell-MRGPRX2/MrgprB2 mediated responses in vitro and in vivo. Specifically, osthole significantly attenuates both the early (Ca 2+ mobilization and degranulation) and delayed phases (chemokine/cytokine production) of mast cell activation. house barge boardsWebOsthole has been reported to regulate various signaling pathways, which in turn modulate several apoptosis-related proteins, cell cycle regulators, protein kinases, transcriptional factors, cytokines, and growth receptors affiliated with inflammation, proliferation and several other ailments. link your iphone windowsWebOct 1, 2024 · Osthole, also known as osthol, is a coumarin derivative found in several medicinal plants such as Cnidium monnieri and Angelica pubescens. It can be obtained … link your iphone to your computerWebOsthole C15H16O3 CID 10228 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity … house barges for sale louisianaWebDec 31, 2024 · Lipopolysaccharydes (LPS) are responsible for the intestinal inflammatory reaction, as they may disrupt tight junctions and induce cytokines (CKs) secretion. Osthole has a wide spectrum of pharmacological effects, thus its anti-inflammatory potential in the LPS-treated Caco-2 cell line as well as in Caco-2/THP-1 and Caco-2/macrophages co … link your iphone to windows 11WebOsthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H 1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Osthole (p<0.0001) and Fexofenadine (p<0.001) inhibit increased HRH-1 mRNA expression induced by histamine in the study group. house bar countertops