Web16 feb. 2024 · 487 Background: The phase 3 JAVELIN Bladder 100 trial (NCT02603432) showed significantly longer overall survival (OS) with avelumab + best supportive care … Web25 ian. 2024 · The phase III JAVELIN Bladder 100 trial met its primary endpoint of overall survival at the planned interim analysis. In this study, patients with previously untreated locally advanced or metastatic urothelial carcinoma whose disease did not progress on induction chemotherapy and who were randomly assigned to receive first-line …
Avelumab Maintenance Therapy for Advanced or …
Web1 iun. 2024 · Introduction. Urothelial carcinoma (UC) is a common cancer that causes substantial morbidity and mortality. In the US, UC is the sixth most-frequent cancer and was responsible for >80,000 new cases and >17,000 deaths in 2024 [1].Risk factors include smoking, older age, male sex, exposure to various industrial/organic chemicals, and … Web16 feb. 2024 · 486 Background: In the phase 3 JAVELIN Bladder 100 trial (NCT02603432), avelumab 1L maintenance therapy + BSC showed significantly longer overall survival (OS) vs BSC alone in patients with advanced UC that had not progressed with 1L platinum-based chemotherapy. We report efficacy and safety results in patients enrolled in Asia. … how to track fedex package by address
Avelumab as second-line therapy for metastatic, platinum-treated ...
WebApolo AB, Infante JR, Hamid O, et al. Avelumab (MSB0010718C; anti-PD-L1) in patients with metastatic urothelial carcinoma from the JAVELIN solid tumor phase 1b trial: analysis of safety, clinical ... Web21 feb. 2024 · 508 Background: For platinum-eligible patients (pts) with advanced UC, 1L cisplatin- or carboplatin-based chemotherapy regimens followed by avelumab maintenance in pts without progression has become the standard of care. This is based on the results of the phase 3 JAVELIN Bladder 100 trial (NCT02603432), which showed significantly … WebLancet Oncol 2024; 18 :599–610. 2. Patel MR, Ellerton J, Infante JR, et al. Avelumab in metastatic urothelial carcinoma after platinum failure (JAVELIN Solid Tumor): pooled results from two expansion cohorts of an open-label, phase 1 trial. Lancet Oncol 2024; 19 :51–64. 3. Bavencio(avelumab) injection. how to track fastag